Minopa
Tolfenamic AcidAntimigraine
Indication:
Minopa is used specifically for relieving the pain of migraine headaches and also recommended for use as an analgesic in post-operative pain, and fever.
Dosage & Administration:
Acute
migraine attacks
Adult: 200 mg when 1st symptoms
appear may be repeated once after 1-2 hr.
Renal impairment: Dose adjustments may be needed. Severe: Avoid.
Mild to moderate pain
Children: A paediatric dosage regimen
has not yet been established. Adult:
100-200 mg tid.
Renal impairment: Dose adjustments
may be needed. Severe: Avoid. It
should be taken with food. Take water/ or immediately after meals.
Preclinical safety data
The therapeutic index for Minopa is
high, and gastrointestinal ulceration and kidney changes have only been seen
with oral doses approximately 6-10 times the maximum therapeutic dose
recommended for Tolfenamic acid.
Special Precautions
Asthma, bronchospasm, bleeding disorders, cardiovascular diseases, history of
peptic ulceration, hypertension, patients with infections, liver, cardiac, or
renal function impairment. Increase water intake or dose reduction to reduce
dysuria. CHF; elderly; lactation.
Preparation:
Minopa Tablet: Each tablet contains Tolfenamic acid BP 200 mg.