Esozol 40

Indication:

·        Treatment of Gastroesophageal Reflux Disease (GERD)

·        Healing of erosive esophagitis

·        Maintenance of healing of erosive esophagitis

·        Symptomatic Gastro esophageal Reflux Disease (GERD)

·        Risk Reduction of NSAID-associated gastric ulcer

·        H. pylori eradication (Triple therapy)

Dosage & Administration:

Recommended adult dosage schedule of Esomeprazole:

Indication		Dose	Frequency
Gastro esophageal Reflux Disease (GERD)
Healing of erosive esophagitis	20 mg or 40 mg		Once daily for 4 to 8 weeks*
Maintenance of healing of erosive esophagitis	20 mg		Once daily **
Symptomatic GERD	20 mg		Once daily for 4 weeks ***
Risk Reduction of NSAID- associated gastric ulcer	20 mg or 40 mg		Once daily for up to 6 months**
H. pylori eradication (Triple therapy)
Esomeprazole	20 mg		Twice daily for 10 days
Amoxicillin	1000 mg		Twice daily for 10 days
Clarithromycin	500 mg		Twice daily for 10 days

Paediatric use (12 years and older)

Short term treatment of GERD: 20 mg or 40 mg once daily for up to 8 weeks.

*The majority of patients are healed within 4 to 8 weeks. For patients who do not heal after 4-8 weeks, an additional 4-8 weeks treatment may be considered.

 ** Controlled studies did not extend beyond six months.

** If symptoms do not resolve completely after 4 weeks, an additional 4 weeks of treatment may be considered.

Preparation:

Esozol 20 Capsule: Each delayed release capsule contains enteric coated pellets of Esomeprazole Magnesium Trihydrate BP equivalent to Esomeprazole 20 mg.

Esozol 40 Capsule: Each delayed release capsule contains enteric coated pellets of Esomeprazole Magnesium Trihydrate BP equivalent to Esomeprazole 40 mg.