Omel® 20

Omeprazole

Capsule

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Indication:

Omeprazole capsules are indicated for the treatment of: reflux esophagitis duodenal ulcer gastric ulcer NSAID-associated gastric and duodenal ulcers or erosions Acid related dyspepsia Zollinger-Ellison syndrome. In the treatment of peptic ulceration, the eradication of H. pylori, as the causative organism, must be a high priority. Accordingly, Omeprazole should be used as part of combination therapy for the eradication of H.pylori. Maintenance- Omeprazole capsules are indicated for maintenance treatment of: reflux esophagitis duodenal ulcer gastric ulcer Zollinger-Ellison syndrome.

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Dosage & Administration:

Duodenal ulcer: 20 mg once daily for 4 weeks. In severe cases, 40 mg once daily for 4 weeks. Gastric ulcer: 20 mg once daily for 8 weeks. In severe cases, 40 mg once daily for 8 weeks. Erosive Reflux Oesophagitis: 20 mg once daily for 4 weeks. For those not fully healed, to be continued for 4 more weeks. Refractory Reflux esophagitis: 40 mg once daily for 8 weeks. Gastro-esophageal reflux disease: 20 mg once daily for 4 weeks, continued for further 4-8 weeks if not fully healed; 40 mg once daily has been given for 8 weeks in gastro-oesophageal reflux disease refractory to other treatment; maintenance 20 mg once daily. Acid reflux disease (long-term management), 10 mg daily increasing to 20 mg once daily if symptoms return. Acid-related dyspepsia: 10-20 mg once daily for 2-4 weeks according to response. Zollinger-Ellison Syndrome: 60 mg once daily, adjusted individually and continued as long as necessary. Most patients will be effectively controlled with 20-120 mg daily. Dosage above 80 mg should be divided and given twice daily.

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Preparation:

In the presence of any alarm symptom (e.g. significant unintentional weight loss, recurrent vomiting, dysphagia, haematemesis or melena) and when gastric ulcer is suspected or present, the possibility of malignancy should be excluded as treatment may alleviate symptoms and delay diagnosis.